,The Government of Canada has published supplemental material following the draft screening assessment of the Flame Retardants Group, focusing on phosphoric acid, triphenyl ester (TPHP; CAS RN 115-86-6) and ethanol, 2-butoxy-, phosphate (TBOEP; CAS RN 78-51-3). While TPHP was previously proposed to meet one or more criteria under section 64 of the Canadian Environmental Protection Act, 1999 (CEPA), TBOEP’s status has been revised based on new data. Updated risk characterization identified developmental effects as the critical endpoint for TPHP, with potential inadequate margins of safety for dermal exposure from nail care products, lubricants, and prolonged contact with foam-containing furniture and child restraint systems. For TBOEP, prolonged dermal exposure from foam-containing products and child restraint systems is considered potentially inadequate. Risk management options under consideration include regulatory and non-regulatory measures to reduce dermal exposure, restrictions in consumer products, and listing TPHP on the Cosmetic Ingredient Hotlist. The ministers are seeking public comments from November 22, 2025, to January 21, 2026, to inform final assessment and risk management decisions. Overall, TPHP and TBOEP are proposed to meet CEPA criteria as substances that may constitute a danger to human health.
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