,What is an Extended Safety Data Sheet (eSDS)?
An Extended Safety Data Sheet (eSDS) is a Safety Data Sheet that goes beyond the standard format by including one or more Exposure Scenarios (ES). Each Exposure Scenario details how a substance can be safely used — defining the Operational Conditions (OC) and Risk Management Measures (RMM) that ensure risks remain controlled.
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Under EU REACH and similar frameworks, eSDS EU REACH service ensures that extended Safety Data Sheets (eSDSs) are developed and provided for substances requiring a Chemical Safety Assessment (CSA). These eSDSs serve as a key communication tool between manufacturers, importers, and downstream users, enabling safe handling, use, and disposal of chemicals throughout the supply chain
Why is an eSDS Important?
In today’s regulatory landscape, ensuring compliance and safety transparency is not optional — it’s essential.
An eSDS helps organizations to:
- Comply with REACH regulations that mandate inclusion of exposure scenarios for hazardous substances.
- Communicate safe use information effectively to downstream users, enabling them to verify that their operational conditions are covered
- Manage risk proactively, implementing appropriate OCs and RMMs to keep exposure below DNEL/PNEC thresholds.
- Be audit-ready, with harmonized documentation linking SDSs, REACH exposure scenario, Chemical Safety Reports (CSR), and IUCLID data.
Our End-to-End eSDS Services
At Freyr, we provide end-to-end eSDS consulting support—from exposure scenario development to downstream user communication. Our multidisciplinary team of toxicologists, regulatory experts, and exposure assessors ensures scientific precision and compliance alignment.
Exposure Scenario (ES) Development
Develop detailed Exposure Scenarios for all substance uses; assessing Operational Conditions (OC) and Risk Management Measures (RMM), aligned with Chemical Safety Report (CSR) and downstream user requirements
eSDS Authoring and Compilation
Integrate Exposure Scenario data into SDS Annex format; prepare extended safety data sheet for mixtures and substances per ECHA guidance; and support tiered approaches- scaling, mapping, and communication of safe use across the supply chain
Chemical Safety Assessment (CSA) Support
Conduct or review CSAs ensuring exposures remain below DNEL/PNEC; apply exposure models like ECETOC TRA, MEASE, ART, CHESAR ; and define safe-use conditions with appropriate control measures for each exposure route.
eSDS Review and Compliance Check
Evaluate eSDS for completeness, accuracy, REACH Annex II compliance; verify consistency between SDS sectons, ES, and CSR ;and update or convert legacy SDS into REACH-compliant formats.
Downstream User (DU) Compliance and Communication
Ensure DU's operational conditions align with supplier eSDS; prepare Downstream User Chemical Safety Assessments(DU CSAs) when needed, and facilitate seamless supply-chain communication for safe-use information.
Fully compliant Extended Safety Data Sheets (eSDS)
Annexed Exposure Scenarios (ES) with defined operational conditions and RMMs
Key Deliverables
Compliance Summary Reports aligned with REACH Annex II
Cross-referenced linkages to Chemical Safety Reports (CSR) and IUCLID datasets
Downstream user compliance documentation and communication templates
Why Choose Freyr for eSDS Support
- End-to-End Expertise: From hazard assessment to CSR preparation and exposure modeling, Freyr provides full-spectrum eSDS support and extended SDS authoring services under one roof.
- Technical Depth: Our team of experienced toxicologists, exposure assessors, and regulatory professionals ensures precision and scientific integrity in every project.
- Global Compliance Coverage: Proven expertise across EU REACH, UK REACH, and emerging frameworks in other regions.
- Efficient Delivery: With harmonized templates, automated workflows, and multi-level quality reviews, Freyr ensures timely, consistent, and audit-ready deliverables.
Let’s Simplify Your eSDS Compliance Journey
Whether you’re a manufacturer, importer, or downstream user, Freyr’s team can help you design, author, or update your eSDS to meet current regulatory standards -ensuring safety, transparency, and compliance across your entire value chain.
Frequently Asked Questions (FAQs) on eSDS Services
We are here to provide you with the information you need quickly and efficiently.
01. What is an Extended Safety Data Sheet (eSDS)?
An eSDS is a Safety Data Sheet that includes Exposure Scenarios (ES) detailing safe use conditions and risk management measures.
02. When is an eSDS required?
It is mandatory under EU REACH for substances that require a Chemical Safety Assessment (CSA REACH).
03. What information does an Exposure Scenario (ES) provide?
It defines Operational Conditions (OC) and Risk Management Measures (RMM) to ensure safe handling and use.
04. Why is an eSDS important for compliance?
It helps organizations comply with REACH regulations, communicate safe-use information, and manage risks proactively.
05. What thresholds are considered in risk management within an eSDS?
DNEL (Derived No-Effect Level) and PNEC (Predicted No-Effect Concentration) values.
06. What services does Freyr offer for eSDS preparation?
Freyr provides ES development, extended SDS authoring services, CSA REACH support, compliance checks, and downstream user communication.
07. How does Freyr ensure scientific accuracy in eSDS development?
By leveraging a multidisciplinary team of toxicologists, regulatory experts, and exposure assessors.
08. What tools are used for exposure modeling in CSA support?
Models such as ECETOC TRA, MEASE, ART, and CHESAR.
09. What are the key deliverables of Freyr’s eSDS services?
Fully compliant eSDS, annexed Exposure Scenarios, compliance summary reports, and downstream user documentation.
10. How does Freyr support downstream user compliance?
By verifying operational conditions, preparing DU CSAs, and facilitating supply-chain communication.
