The Cosmetic Ingredient Review (CIR) Expert Panel conducted a detailed scientific evaluation of Polyacrylate-13, a synthetic polymer widely used in cosmetic formulations. Known for its ability to act as a film former, viscosity enhancer, and stabilizer, Polyacrylate-13 improves texture, spreadability, and overall product performance in skincare and haircare applications. The assessment carefully examines the ingredient’s chemical identity, manufacturing methods, and potential impurities, including residual monomers. It also reviews reported use concentrations across various cosmetic categories to determine realistic consumer exposure levels. A broad range of toxicological data is analyzed, including studies on dermal and ocular irritation, skin sensitization, and repeated-dose exposure. Human patch testing and formulation-based evaluations further support the safety review under practical conditions of use. Given that Polyacrylate-13 is primarily applied topically and is not expected to penetrate deeply into the skin, systemic exposure is considered minimal. Based on the available scientific evidence, the draft assessment indicates no significant safety concerns at current usage levels, pending final expert panel conclusions.