,In its draft risk evaluation of 1,2-dichloroethane, the U.S. Environmental Protection Agency (EPA) identified significant health concerns across multiple exposure scenarios. The assessment found increased cancer risks for workers through inhalation and dermal contact, as well as for Occupational Non-Users (ONUs) and nearby communities exposed via inhalation. The draft also highlighted potential non-cancer effects, including renal impacts from dermal exposure in workers, olfactory effects in workers and ONUs following acute inhalation, and male reproductive effects from intermediate and chronic inhalation exposures. Based on its analysis of 20 conditions of use, the EPA reached a preliminary determination that 15 uses present an unreasonable risk to human health, particularly for workers and ONUs. These findings will inform the next stages of the TSCA risk evaluation process and may lead to risk management measures aimed at reducing harmful exposures to this industrial chemical.
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